The Thin, Soft, Miniaturized System (TSMS) integrates a conformal piezoelectric sensor array, active pressure adaptation module, signal processing module, and an advanced machine learning algorithm, enabling seamless, continuous wireless monitoring of ambulatory artery blood pressure (BP) in a wearable form. The system's high level of integration ensures a comfortable and user-friendly experience. Its robust interfacial stability and advanced data model contribute to exceptional measurement accuracy, rivaling that of professional medical equipment. With TSMS, users can realize accurate and convenient monitoring of their ambulatory artery BP at home, without any other instruments involved.