Mattress with different designed air cells performs pressure redistribution with anti-decubitus prevention. Reduces the most risk location for bedsores, an innovative 3-layer cell around the sacrum prevents the trouble situation regarding body from sinking into the mattress. Features sliding prevention, body bottoming out prevention and the ventilation system to lower the high humidity caused by sweat. Adjusts the pressure automatically to match the body weight of the patient/ resident increased comfortable. With the mattress air-leak detection system, the warning sound and LED indicate to alert the caregivers.